Aspergillus fumigatus alkaline protease 1 (Alp1/Asp f13) in the airways correlates with asthma severity

Autor:	Michel Laviolette, Janyce A. Sugui, Ming Zhao, Kirk M. Druey, Kyung Joo Kwon Chung, Sabrina Biardel, Nariman Balenga, Seyedmojtaba Seyedmousavi, Trisha Basu
Rok vydání:	2017
Předmět:	0301 basic medicine medicine.medical_treatment Immunology Respiratory Mucosa medicine.disease_cause Severity of Illness Index Article Aspergillus fumigatus 03 medical and health sciences 0302 clinical medicine Allergen Bacterial Proteins Severity of illness Endopeptidases medicine Immunology and Allergy Humans skin and connective tissue diseases Asthma Protease biology business.industry Alkaline protease Allergens biology.organism_classification medicine.disease respiratory tract diseases 030104 developmental biology 030228 respiratory system Immunohistochemistry Allergic bronchopulmonary aspergillosis business
Zdroj:	The Journal of allergy and clinical immunology. 141(1)
ISSN:	1097-6825
Popis:	Summary A fungal protease (Alp1/ Asp f13 ) from Aspergillus fumigatus was detected in the airways of subjects with asthma but not controls, which correlated strongly with disease severity, respiratory dysfunction, and steroid use.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d1f17dd1d8dbfaf91fa2044b3706fc https://pubmed.ncbi.nlm.nih.gov/28882610 Zobrazit plný text záznamu Full Text from ScienceDirect