The Impact of Pretreatment Low Body Mass Index on Cause-Specific Mortality in Patients with Squamous Cell Carcinoma of the Oral Cavity

Autor: Kyoko Kurioka, Shin Rin, Mitsunobu Otsuru, Tomohumi Naruse, Takumi Hasegawa, Nobuhiro Yamakawa, Shin-ichi Yamada, Eiji Hirai, Kozo Yamamoto, Michihiro Ueda, Tadaaki Kirita, Masaya Akashi, Hiroshi Kurita, Yoichi Ohiro, Masaya Okura
Rok vydání: 2022
Předmět:
Zdroj: Nutrition and cancer.
ISSN: 1532-7914
Popis: The association between the pretreatment body mass index (BMI) and oral squamous cell carcinoma (SCC) outcomes is controversial. We aimed to examine the association between BMI and cause-specific mortality due to cancer of the oral cavity and patterns of failure that correlate with increased mortality. We enrolled 2,023 East Asian patients in this multicenter cohort study. We used the cumulative incidence competing risks method and the Fine-Gray model to analyze factors associated with cause-specific mortality, local recurrence, regional metastasis, and distant metastasis as first events. The median follow-up period was 62 mo. The 5-year cause-specific mortality for patients with underweight was 25.7%, which was significantly higher than that for patients with normal weight (12.7%
Databáze: OpenAIRE