Newborns and low to moderate prenatal environmental lead exposure: might fathers be the key?
| Autor: | Jenaro Astray, María José González, Jesús Vioque, Ángel Asensio, Esther García-Esquinas, Beatriz Pérez-Gómez, Mario Antonio Fernández, Andrés Iriso, Concha de Paz, Mercedes Martínez, Margot Cisneros, José Frutos García, América de León, Ana María Pérez-Meixeira, J. Sanz, José Miguel García-Sagredo, Gonzalo López-Abente, Marina Pollán, Nuria Aragonés, Elisa Gil, Amparo de Santos |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Urban Population Health Toxicology and Mutagenesis Physiology Pregnancy medicine Environmental Chemistry Humans Fetus business.industry Infant Newborn Infant General Medicine Environmental exposure Anatomy Odds ratio Environmental Exposure medicine.disease Fetal Blood Pollution Confidence interval Paternal Exposure Lead Spain Cord blood Gestation Environmental Pollutants Female business Biomarkers Environmental Monitoring |
| Zdroj: | Environmental science and pollution research international. 21(13) |
| ISSN: | 1614-7499 |
| Popis: | This study is part of the BioMadrid Project, a bio-monitoring study designed to assess pollutants in the environment surrounding children born in the Madrid region. Our aim in this report is to evaluate the association between prenatal lead exposure and fetal development using three biological samples (maternal and paternal blood lead at around 34 weeks of gestation as well as cord blood lead levels), three biomarkers of effect in cord blood peripheral lymphocytes (micronucleus in binucleated cells, nucleoplasmic bridges, and nuclear buds), and different anthropometrical characteristics at birth. Maternal and cord blood lead were not associated with newborn measurements or genotoxicity biomarkers. In contrast, increases in father blood lead were coupled with lower weight (mean difference (MD), −110.8 g; 95 % confidence intervals (95%CI), −235.6 to 6.00; p |
| Databáze: | OpenAIRE |
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