Combined alterations in MAPK pathway genes, CDKN2A/B and ATRX characterize anaplastic pilocytic astrocytoma

Autor: Kratz, Annekathrin, Sahm, Felix, Schrimpf, Daniel, Jones, David T., Reuss, David, Koelsche, Christian, Huang, Kristin, Wefers, Annika K., Hovestadt, Volker, Gramatzki, Dorothee, Felsberg, Joerg, Koch, Arend, Thomale, Ulrich-W., Reifenberger, Guido, Becker, Albert, Hans, Volkmar, Prinz, Marco, Staszewski, Ori, Acker, Till, Dohmen-Scheufler, Hildegard, Hartmann, Christian, Mueller, Wolf, Tuffaha, Muin S. A., Paulus, Werner, Heß, Katharina, Brokinkel, Benjamin, Schittenhelm, Jens, Monoranu, Camelia-Maria, Kessler, Almuth Friederike, Loehr, Mario, Buslei, Rolf, Deckert, Martina, Mawrin, Christian, Kohlhof, Patricia, Hewer, Ekkehard, Olar, Adriana, Rodriguez, Fausto, Giannini, Caterina, NageswaraRao, Amulya A., Weller, Michael, Pohl, Ute, Brandner, Sebastian, Pfister, Stefan M., Von Deimling, Andreas, Capper, David
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Joint-Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) and the Scandinavian Neuropathological Society (SNS); 20160922-20160924; Hamburg; DOC16dgnnP45 /20160914/
DOI: 10.3205/16dgnn46
Popis: Introduction: Tumors with histological features of pilocytic astrocytoma but with increased mitotic activity and additional high grade features (i.e. microvascular proliferation, necrosis) have been designated anaplastic pilocytic astrocytomas (APA). Patients with such tumors are thought to have an [for full text, please go to the a.m. URL]
Joint-Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) and the Scandinavian Neuropathological Society (SNS)
Databáze: OpenAIRE