Occurrence of IgM antibodies against BK and JC polyomaviruses during pregnancy
| Autor: | D V Coleman, P. E. Gibson, S. D. Gardner, AnneM. Field |
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| Rok vydání: | 1981 |
| Předmět: |
Cord
Igm antibody viruses Antibodies Viral medicine.disease_cause Pathology and Forensic Medicine Serology Pregnancy Animals Humans Medicine Pregnancy Complications Infectious Maternal-Fetal Exchange biology business.industry Infant Newborn General Medicine Fetal Blood medicine.disease BK virus Tumor Virus Infections Immunoglobulin M BK Virus Cord blood Immunology biology.protein Female Antibody Polyomavirus business Research Article |
| Zdroj: | Journal of Clinical Pathology. 34:674-679 |
| ISSN: | 0021-9746 |
| DOI: | 10.1136/jcp.34.6.674 |
| Popis: | In a serological survey of 430 pregnant women 45 had high or rising titres of BK-virus haemagglutination-inhibiting antibodies. The presence of BK-virus-specific IgM was confirmed in 10 of these women. No BK-virus-specific IgM was detected in the samples of cord blood from the babies born to these women. The sera from 40 women known to be excreting inclusion-bearing cells during pregnancy were tested for the presence of BK-virus and JC-virus-specific IgM and IgG. The presence of BK-virus-specific IgM was confirmed in three cases and JC-virus-specific IgM in seven cases. Specific IgM persisted for several months in some pregnant women. No Bk-virus-specific IgM was detected in any of the samples of cord blood from the babies born to these women with evidence of polyomavirus infection. No JC-virus-specific IgM was detected in 36 out of 37 of the cord bloods; however, in one it is possible that minute amounts of JC-virus-specific IgM were present. |
| Databáze: | OpenAIRE |
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