Polymorphic phospholipid phase transitions as tools to understand peptide-lipid interactions
| Autor: | H. Tournois, B. de Kruijff |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Phase transition
Lipid Bilayers Molecular Sequence Data Molecular Conformation Synthetic membrane Phospholipid Peptide Membrane Fusion complex mixtures Biochemistry Melittin Membrane Lipids chemistry.chemical_compound Gramicidin A Amino Acid Sequence Molecular Biology Phospholipids chemistry.chemical_classification Bilayer Organic Chemistry Gramicidin Cell Biology Melitten Membrane Models Chemical chemistry lipids (amino acids peptides and proteins) Peptides |
| Zdroj: | Chemistry and Physics of Lipids. 57:327-340 |
| ISSN: | 0009-3084 |
| DOI: | 10.1016/0009-3084(91)90084-o |
| Popis: | The effect of peptides on bilayer → non-bilayer phase transitions can be used as a tool to investigate the molecular aspects of peptide-lipid interactions. In this contribution the action on membranes of the peptide antibiotic gramicidin A and the bee venom component melittin are compared. Although the know structures and locations of these peptide upon membrane binding are very different, their actions on membranes show striking parallels. A general model is proposed that explains the seemingly complex peptide-lipid interactions by making use of simple concepts. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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