ECT Anesthesia: The Lighter the Better?
| Autor: | H.-J. Bender, F. J. Andres, Fritz A. Henn, E. M. Muñoz-Canales, Alexander Sartorius, Bertram Krumm, A. Krier |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Concordance medicine.medical_treatment Electroencephalography behavioral disciplines and activities Electroconvulsive therapy Heart Rate mental disorders Heart rate medicine Full remission Humans Anesthesia Pharmacology (medical) Ictal Electroconvulsive Therapy Major depressive episode Aged Psychiatric Status Rating Scales Depressive Disorder Major medicine.diagnostic_test General Medicine Middle Aged Psychiatry and Mental health Anesthetic Regression Analysis Female medicine.symptom Psychology medicine.drug |
| Zdroj: | Pharmacopsychiatry. 39:201-204 |
| ISSN: | 1439-0795 0176-3679 |
| DOI: | 10.1055/s-2006-950395 |
| Popis: | BACKGROUND: Electroconvulsive therapy (ECT) is a most effective treatment for patients with major affective disorders. The influence of anesthetic drugs on seizure "adequacy" or on treatment success has not been systematically investigated. METHODS: A bispectral EEG index score (BIS) was used to identify the depth of anesthesia during ECT. Our study included 22 major depressive episode (MDE) patients expanding to 219 ECTs (05/05-01/06) with no limitations of concurrent medication. RESULTS: Fourteen out of the 22 patients showed full remission. Individual number of ECT sessions needed to reach full remission correlated negatively with mean pre-ECT BIS values (p=0.001). Additionally, using a repeated measurement regression analysis significant correlations were found for pre-ECT BIS versus motor response time, seizure concordance, ictal coherence and peak heart rate. CONCLUSION: The results of our study suggest BIS-levels as a predictor of faster ECT response. Controlling BIS-levels before stimulation may have an additional effect on treatment success. |
| Databáze: | OpenAIRE |
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