Genetically modified species in research: Opportunities and challenges for the histology core laboratory

Autor:	Mary Sturm, David K. Meyerholz, Alicia K. Olivier, Katherine N. Gibson-Corley, Paul W. Naumann, Christine Hochstedler, Janis R Rodgers, Adam Goeken
Rok vydání:	2012
Předmět:	Protocol (science) Histology Genetically engineered media_common.quotation_subject Physiology Translational research Research needs Research opportunities Biology Data science Article Genetically modified organism Medical Laboratory Technology Quality (business) Anatomy Core laboratory media_common
Zdroj:	Journal of histotechnology. 35(2)
ISSN:	0147-8885
Popis:	Translational research using animal models has traditionally involved genetically modified rodents; however, there is increasing use of other novel genetically engineered species. As histology laboratories interface with researchers studying these novel species there will be many situations in which protocols will need to be adapted to the species, model and research goals. This paper gives examples of protocol adaptations to meet research needs and addresses common considerations that should be addressed for all research tissues submitted to the histotechnology laboratory. Positioning the histotechnologist, as well as the investigator, to meet the challenges associated with novel research models will help maximize research efficacy and quality.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b85a3506b742af5080a4cc3813af9f https://pubmed.ncbi.nlm.nih.gov/22904582 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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