Open-angle glaucoma in a rural and urban population in Eastern India—the Hooghly river glaucoma study
| Autor: | Subhrangshu Sengupta, Chandrima Paul, Sumit Choudhury, Souvik Banerjee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Rural Population Intraocular pressure Open angle glaucoma genetic structures Urban Population Cross-sectional study Population Gonioscopy Glaucoma open-angle glaucoma India Logistic regression Risk Assessment Central corneal thickness 03 medical and health sciences 0302 clinical medicine Age Distribution Risk Factors medicine Prevalence Humans Sex Distribution education Intraocular Pressure Aged education.field_of_study medicine.diagnostic_test business.industry Middle Aged medicine.disease eye diseases Frequency doubling technology perimetry Ophthalmology Cross-Sectional Studies 030221 ophthalmology & optometry Original Article Female sense organs frequency-doubling technology perimetry Visual Fields business 030217 neurology & neurosurgery Glaucoma Open-Angle Demography |
| Zdroj: | Indian Journal of Ophthalmology |
| ISSN: | 1998-3689 0301-4738 |
| Popis: | Purpose: Glaucoma is the leading cause of irreversible blindness in the world. The current study aims to estimate prevalence, features, and associations of open angle glaucoma (OAG) in a rural and urban East Indian population. Methods: This is a population based cross sectional study with two arms, rural (28 contiguous villages from 13 Gram Panchayats in Balagarh Police Station, Hooghly district) and urban (Kolkata). Individuals residing in the study area aged 40 years and above were included using multistage random cluster sampling. All subjects underwent a detailed ophthalmic examination at our base hospitals including applanation tonometry, ultrasound pachymetry, gonioscopy, and frequency doubling technology perimetry. The primary outcome was the prevalence of POAG (95% CI). Age and gender specific prevalence estimates were calculated. Multiple logistic regressions were used to analyze the risk factors. Results: Data from 7128 and 6964 subjects aged 40 years or older from Kolkata city and Hooghly district, respectively were analyzed. In the urban population, 2.10% (95% CI: 1.99–2.21%) had POAG and 0.15% (95% CI: 0.13–0.17%) had secondary OAG. In the rural population, 1.45% (95% CI: 0.59–2.31%) had POAG and 0.10 ± 0.03% (95% CI: 0.07–0.13%) had secondary OAG. Conclusion: The study concludes that higher age, higher vertical cup disc ratio (VCDR), and lower central corneal thickness (CCT) are important independent predictors of OAG and emphasizes that increased intraocular pressure (IOP) is not POAG. Gonioscopy, disc evaluation, and screening perimetry need to be incorporated in the detection protocol for glaucoma if we intend to lighten the burden of blindness due to glaucoma. |
| Databáze: | OpenAIRE |
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