Tumor Infiltration Depth as a Prognostic Parameter for Nodal Metastasis in Oral Squamous Cell Carcinoma
| Autor: | Urvashi Ashwin Shetty, Satadru Roy, Padmaraj Hegde, B. Rajendra Prasad, Tripthi Shetty |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Oncology
squamous cell carcinoma medicine.medical_specialty Lymphatic metastasis Study groups Prognostic factor Review Article 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Basal cell 030223 otorhinolaryngology business.industry Nodal metastasis Patient survival oral cancer tumor invasion medicine.disease tumor infiltration depth Occult stomatognathic diseases 030220 oncology & carcinogenesis business Infiltration (medical) |
| Zdroj: | International Journal of Applied and Basic Medical Research |
| ISSN: | 2248-9606 2229-516X |
| Popis: | Oral squamous cell carcinoma (OSCC) has locoregional evolution, with frequent neck involvement. Significant number of studies have been undertaken to assess the parameters for treatment of N0 neck patients with a high likelihood of harboring occult node metastases. Many studies have indicated tumor infiltration depth (or tumor thickness) as one of the most important criteria in determining the further management. Growing evidence in the literature shows that tumor infiltration depth is a reliable parameter for predicting regional node involvement and patient survival in OSCC. The substantial agreement among authors, despite the lack of comparable study groups, of measurement techniques, and cutoff values paradoxically enforced its reliability. Further studies are clearly awaited to reach a consensus on these topics to develop therapy protocols that are also based on this parameter. This article is an attempt to substantiate the use of tumor infiltration depth as a prognostic factor for nodal metastasis in OSCC. |
| Databáze: | OpenAIRE |
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