Why Calcium-Stimulated Adenylyl Cyclases?

Autor:	Daniel R. Storm, Gregory D. Ferguson
Rok vydání:	2004
Předmět:	Neurons ADCY6 Gs alpha subunit Physiology ADCY9 chemistry.chemical_element Long-term potentiation Calcium Biology ADCY3 ADCY10 Calmodulin nervous system Biochemistry chemistry Animals cAMP-dependent pathway Adenylyl Cyclases Signal Transduction
Zdroj:	Physiology. 19:271-276
ISSN:	1548-9221 1548-9213
Popis:	The Ca2+/calmodulin-stimulated adenylyl cyclases, AC1 and AC8, play a critical role in several forms of neuroplasticity, including long-lasting long-term potentiation (L-LTP) and long-term memory (LTM). By coupling neuronal activity and Ca2+increases to the production of cAMP, AC1 and AC8 activate cAMP-dependent signal transduction and transcriptional pathways critical for L-LTP and LTM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b0106a6345570595cd2063ab32b410 https://doi.org/10.1152/physiol.00010.2004 Zobrazit plný text záznamu