Carboxylic Acid-Catalyzed Highly Efficient and Selective Hydroboration of Alkynes with Pinacolborane

Autor:	Tienan Jin, Yoshinori Yamamoto, Naoki Asao, Hon Eong Ho
Rok vydání:	2014
Předmět:	chemistry.chemical_classification Hydroboration chemistry Carboxylic acid Organic Chemistry Organic chemistry Metal catalyst Physical and Theoretical Chemistry Biochemistry Catalysis
Zdroj:	Organic Letters. 16:4670-4673
ISSN:	1523-7052 1523-7060
Popis:	We have demonstrated for the first time that carboxylic acids are able to catalyze the direct hydroboration of various terminal and internal alkynes with pinacolborane without using any metal catalysts. This unprecedented catalytic hydroboration exhibits a broad functional groups compatibility, giving the corresponding alkenyl diboronates and monoboronates in good to high yields with exclusive regio- and stereoselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ad6b790bb345d87b8cfd4dafdf83b6 https://doi.org/10.1021/ol502285s Zobrazit plný text záznamu