Diffuse Brainstem Glioma in a Patient with Laurence-Moon-(Bardet-)Biedl Syndrome
| Autor: | Yukitaka Ushio, Masato Kochi, Masaki Miura, Kazumichi Yamada, Haruhiko Miyayama, Naomi Sakashita |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Adolescent Autopsy Central nervous system disease Fatal Outcome Glioma medicine Brain Stem Neoplasms Humans Laurence-Moon Syndrome medicine.diagnostic_test business.industry Pons Varolii Brain Magnetic resonance imaging Combination chemotherapy General Medicine medicine.disease Magnetic Resonance Imaging Pons nervous system diseases Pediatrics Perinatology and Child Health Female Surgery Neurology (clinical) Brainstem Glioblastoma business |
| Zdroj: | Pediatric Neurosurgery. 33:323-327 |
| ISSN: | 1423-0305 1016-2291 |
| DOI: | 10.1159/000055979 |
| Popis: | An autopsy case of a patient with diffuse brainstem glioma associated with Laurence-Moon-(Bardet-)Biedl syndrome is described. The subject was a 25-year-old woman who had been suffering from mental retardation, pigmented retinopathy, obesity, hexadactyly, amenorrhea and renal cysts. She developed dizziness, headache and consequent consciousness disturbance. Magnetic resonance images disclosed marked swelling of the pons without contrast enhancement. By means of combined chemotherapy and radiation, she survived for 15 months. Histopathological diagnosis for postmortem specimens obtained from the brainstem was glioblastoma multiforme. No pathogenetic association between the syndrome and brainstem gliomas is known, and the literature contains no cases of patients with this coincidence. |
| Databáze: | OpenAIRE |
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