Urinary creatine as a potential marker of testicular damage: effect of vasectomy
| Autor: | Ruth P. Draper, John A. Timbrell |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Urinary system Radioimmunoassay Cadmium chloride Biology Testicle Toxicology Creatine Rats Sprague-Dawley chemistry.chemical_compound Hydroxybutyrate Dehydrogenase Vas Deferens Cadmium Chloride Internal medicine Testis Vasectomy medicine Animals Testosterone Aspartate Aminotransferases Creatinine L-Lactate Dehydrogenase Vas deferens Alanine Transaminase Rats Isoenzymes Proteinuria medicine.anatomical_structure Endocrinology chemistry Alanine transaminase Toxicity biology.protein Carcinogens Ethylene Glycols Biomarkers Immunosuppressive Agents |
| Zdroj: | Reproductive toxicology (Elmsford, N.Y.). 10(1) |
| ISSN: | 0890-6238 |
| Popis: | The concentrations of creatine in the rat testis are high compared to all other tissues except muscle. The total creatine content of the testis is also considerably greater than all organs examined except muscle. Vasectomised male rats were given 2-methoxyethanol or cadmium chloride at doses that caused testicular damage. In the vasectomised rats, testicular damage still resulted in significant creatinuria. This indicates the creatine reaches the urine at least partly via the blood stream and not via the vas deferens. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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