Occurrence of highly oxygen-substituted androgens in hemofiltrates of uremic patients
| Autor: | Helga Ludwig-Köhn, Dieter Matthaei, H. V. Henning, Gerhard Spiteller, F. Scheler, Astrid Sziedat |
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| Rok vydání: | 1980 |
| Předmět: |
0303 health sciences
Chromatography Chemistry medicine.medical_treatment chemistry.chemical_element Fraction (chemistry) Biochemistry Oxygen Gas Chromatography-Mass Spectrometry Steroid 03 medical and health sciences Hemofiltrates 0302 clinical medicine Renal Dialysis 030220 oncology & carcinogenesis medicine Molecular Medicine Organic chemistry Humans Gas chromatography–mass spectrometry Androstanes Spectroscopy 030304 developmental biology Uremia |
| Zdroj: | Biomedical mass spectrometry. 7(7) |
| ISSN: | 0306-042X |
| Popis: | The steroid fraction of hemofiltrate contains a large number of unknown steroids, which were separated by a combination of different chromatographic procedures and finally characterized by gas chromatography mass spectrometry. Besides different isomeric 3,16,17-trihydroxyandrostanes in a rather polar fraction a 3,16,17-trihydroxy-11-ketoandrostane was detected, obviously the first naturally occurring representative of 3,11,16,17 -oxygen-tetrasubstituted androstanes. |
| Databáze: | OpenAIRE |
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