Coronary artery atherosclerosis associated with shift work in chemical plant workers by using coronary CT angiography
| Autor: | Hyeong-Min Lim, Keun-Ho Jang, WonYang Kang, Won-Ju Park, Ji-Sung Ahn, Jai-Dong Moon, Soo-Hyeon Kim, Do-Hyeong Gwon |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Employment Male Work medicine.medical_specialty Computed Tomography Angiography Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Shift work Coronary artery disease 03 medical and health sciences 0302 clinical medicine Occupational Exposure Work Schedule Tolerance Diabetes mellitus Internal medicine Odds Ratio Humans Medicine 030212 general & internal medicine Life Style Computed tomography angiography medicine.diagnostic_test business.industry Public Health Environmental and Occupational Health Odds ratio Middle Aged Atherosclerosis medicine.disease Coronary Vessels Occupational Diseases Stenosis Logistic Models medicine.anatomical_structure Chemical Industry Multivariate Analysis Angiography Cardiology Waist Circumference business Artery |
| Zdroj: | Occupational and Environmental Medicine. 73:501-505 |
| ISSN: | 1470-7926 1351-0711 |
| DOI: | 10.1136/oemed-2015-103118 |
| Popis: | Objectives The aim of this study was to investigate whether shift work is related to elevated risk of coronary artery disease (CAD) by determining the coronary artery calcium (CAC) score and the presence of coronary artery stenosis by using coronary artery CT angiography (CCTA). Methods In this study, 110 male workers participated and underwent a CCTA examination for CAC scoring, which represents coronary artery plaque, and were evaluated for luminal stenosis. All of the participants were working in the same chemical plant, of whom 70 worked day shifts and 40 worked rotating shifts. Results In a multivariate logistic regression analysis, including age, smoking status, alcohol consumption, regular exercise and waist circumference, shift work was associated with a 2.89-fold increase in the odds of developing coronary plaque compared with day work (OR, 2.89; 95% CI 1.07 to 7.82). The association between shift work and coronary plaque was strong after adjustment for age, low-density lipoprotein cholesterol, hypertension and diabetes mellitus (OR, 2.92; 95% CI 1.02 to 8.33). In addition, the number of years of shift work employment was associated with coronary plaque. However, no association was found between shift work and coronary artery stenosis. Conclusions Shift work could induce CAD onset via the atherosclerotic process, and shift work employment duration was associated with an increased risk of atherosclerosis in male workers. |
| Databáze: | OpenAIRE |
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