Durability of immune responses after boosting in Ad26.COV2.S-primed healthcare workers
| Autor: | Sablerolles, R.S.G., Rietdijk, W.J.R., Goorhuis, A., Postma, D.F., Visser, L.G., Schmitz, K.S., Geers, D., Bogers, S., Haren, E. van, Koopmans, M.P.G., Dalm, V.A.S.H., Kootstra, N.A., Huckriede, A.L.W., Akkerman, R., Beukema, M., Lafeber, M., Baarle, D. van, Vries, R.D. de, Kuy, P.H.M. van der, GeurtsvanKessel, C.H., SWITCH Res Grp |
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| Přispěvatelé: | Translational Immunology Groningen (TRIGR), Microbes in Health and Disease (MHD), Pharmaceutical Technology and Biopharmacy, Pharmacy, Internal Medicine, Virology, Immunology, Infectious diseases, AII - Infectious diseases, APH - Aging & Later Life, APH - Global Health, Experimental Immunology |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 76(3). Oxford University Press Clinical Infectious Diseases, 76(3), e533-e536. OXFORD UNIV PRESS INC Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 76(3):ciac495, e533-e536. Oxford University Press Clinical infectious diseases, 76(3), e533-e536. Oxford University Press |
| ISSN: | 1058-4838 |
| DOI: | 10.1093/cid/ciac495 |
| Popis: | The emergence of SARS-CoV-2 variants raised questions regarding the durability of immune responses after homologous or heterologous boosters after Ad26.COV2.S-priming. We found that SARS-CoV-2–specific binding antibodies, neutralizing antibodies, and T cells are detectable 5 months after boosting, although waning of antibodies and limited cross-reactivity with Omicron BA.1 was observed. |
| Databáze: | OpenAIRE |
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