Autor:	Jerome A. Roth, Silvia Ponzoni, Michael Aschner
Rok vydání:	2012
Předmět:	Manganese Chemistry Manganese Poisoning Neurodegeneration Neurotoxicity Parkinson Disease Mitochondrion medicine.disease Article Parkin Mitochondria Manganese homeostasis medicine Homeostasis Humans Neuroscience
Zdroj:	Metal Ions in Life Sciences ISBN: 9789400755604
DOI:	10.1007/978-94-007-5561-1_6
Popis:	The present review addresses issues pertinent to Mn accumulation and its mechanisms of transport, its neurotoxicity and mechanisms of neurodegeneration. The role of mitochondria and glia in this process is emphasized. We also discuss gene x environment interaction, focusing on the interplay between genes linked to Parkinson’s disease (PD) and sensitivity to Mn.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28363517d9273e9593cc5ff27a535ac https://doi.org/10.1007/978-94-007-5561-1_6 Zobrazit plný text záznamu