Hyperglycemia and diabetes mellitus in chagasic and non-chagasic women
| Autor: | Selma Freire de Carvalho da Cunha, Vicente de Paula Antunes Teixeira, Vitorino Modesto dos Santos, Taciana Arruda Modesto dos Santos, Jenner Arruda Modesto dos Santos, Daniel Ferreira da Cunha, Lister Arruda Modesto dos Santos, Jaqueline Pontes Monteiro |
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| Jazyk: | portugalština |
| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Autonomic dysfunction Disease Asymptomatic Gastroenterology Hiperglicemia Doença de Chagas Diabetes mellitus Internal medicine parasitic diseases Medicine Trypanosoma cruzi biology business.industry Disfunção autonômica Retrospective cohort study medicine.disease biology.organism_classification University hospital Chagas' disease Infectious Diseases Endocrinology Hyperglycemia Parasitology Analysis of variance medicine.symptom business Body mass index |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical v.32 n.5 1999 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Vol 32, Iss 5, Pp 489-496 (1999) Revista da Sociedade Brasileira de Medicina Tropical, Volume: 32, Issue: 5, Pages: 489-496, Published: OCT 1999 |
| Popis: | Estudo retrospectivo de 647 mulheres com idade340 anos, atendidas no Hospital-Escola da FMTM, Uberaba-MG. As três sorologias para a doença de Chagas foram negativas nas controles (n = 285) e positivas nas chagásicas (n = 362), que foram classificadas nas formas indeterminada (n = 125), megas (n = 58) e cardíaca (n = 179). Diabetes mellitus foi definido por duas glicemias em jejum3140mg/dl e hiperglicemia por glicemia em jejum > 110mg/dl. Os grupos foram comparados pelos testes do c2, análise de variância, "t" de Student, Kruskal-Wallis e Mann-Whitney, considerando-se significativo p < 0,05. chagásicas e controles estavam pareadas quanto à idade, o índice de massa corporal e a cor. Diabetes mellitus foi mais freqüente na forma cardíaca (15,1%), comparada com as controles (7,4%), megas (7,4%) e assintomáticas (5,6%), o mesmo ocorrendo com a hiperglicemia (37,4%, 26,7%, 25,9% e 27,2%, respectivamente), achados que estão de acordo com possível desnervação parassimpática causada pelo Trypanosoma cruzi e conseqüente predomínio da atividade simpática. Medical records of340 years old female seen at University Hospital from June/93 to July/95 were submitted to a cross-sectional study. According to Chagas' disease tests, patients were divided into chagasic (n = 362) and controls (n = 285). Diabetes mellitus was defined on the basis of two fasting blood glucose levels3140mg/dl and hyperglycemia as fasting blood glucose > 110mg/dl. Chagasic patients were divided into groups with the cardiac form of the disease (n = 179), with megas (n = 58), and asymptomatic (n = 125). Groups were compared by the c2 test, analysis of variance, Student's "t" test, and Kruskal-Wallis and Mann-Whitney tests. A significant difference was assumed when p < 0.05. Chagasic and control groups were matched for age, white color and body mass index. Diabetes mellitus was more prevalent in patients with the cardiac form of Chagas' disease than in controls, or patients with the megas or the asymptomatic form (15.1%, 7.4%, 7.4%, and 5.6%, respectively); the same was observed for hyperglycemia (37.4%, 26.7%, 25.9%, 27.2%), in agreement with the hypothesis that the reduced parasympathetic activity caused by Trypanosoma cruzi leads to relative sympathetic hyperactivity. |
| Databáze: | OpenAIRE |
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