The frozen elephant trunk technique in an emergency: THORAFLEX French National Registry offers new insights
Autor: | Xavier Chaufour, Bertrand Marcheix, Yuthiline Chabry, Jean-Marc Alsac, Paul Achouh, Charles-Henri Gautier, Thierry Caus, Jean Porterie, Vito G. Ruggieri, Fabien Koskas, Thierry Reix, Joseph Nader |
---|---|
Rok vydání: | 2020 |
Předmět: |
Pulmonary and Respiratory Medicine
Aortic dissection Acute aortic syndrome Aorta medicine.medical_specialty Elephant trunks business.industry medicine.medical_treatment EuroSCORE General Medicine 030204 cardiovascular system & hematology medicine.disease Prosthesis Surgery 03 medical and health sciences 0302 clinical medicine 030228 respiratory system medicine.artery medicine National registry Cardiology and Cardiovascular Medicine Paraplegia business |
Zdroj: | European Journal of Cardio-Thoracic Surgery. 59:458-466 |
ISSN: | 1873-734X 1010-7940 |
Popis: | OBJECTIVES Our goal was to study the immediate outcome after an emergency frozen elephant trunk procedure with a Thoraflex™ Hybrid prosthesis (THP) in patients included in the EPI-Flex national registry and operated on in 21 French centres. METHODS All patients operated on in France between April 2016 and April 2019 for acute aortic syndromes and who had an frozen elephant trunk procedure with a THP were included in the study. The main end point was in-hospital mortality. The secondary end point was neuromorbidity, including paraplegia. The evolution of the main end point was monitored using a variable life-adjusted display graph with cumulative sum derivatives in order to stop inclusions in case the observed mortality became out of range compared to an expected mortality between 15% and 20%. RESULTS Enrolment ended on the scheduled date and included 109 patients. Most cases (54%) were performed at 3 centres, where more than 10 THP each were implanted (10–26). The observed mortality in the large-volume centres (22%) was comparable to that observed in the low-volume centres (20%). The individually risk-adjusted cumulative sum revealed that observed in-hospital mortality was statistically in line with that predicted by the log EuroSCORE. Analysis of the secondary end point revealed 8% cases of paraplegia, all of which appeared after treatment of the thoracic type A aortic dissection. CONCLUSIONS In France, THP for emergency frozen elephant trunk surgery outside high-volume centres did not result in excessive in-hospital deaths. However, a word of caution must be expressed regarding the prevention of medullar ischaemia even in emergency aortic surgery. |
Databáze: | OpenAIRE |
Externí odkaz: |