Efficacy of ECT in depression: a meta-analytic review
Autor: | Valéria de Queiroz, Giovanni B. Cassano, Stefano Pini, Daniel Pagnin |
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Jazyk: | angličtina |
Rok vydání: | 2004 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Neuroscience (miscellaneous) Statistical difference Placebo behavioral disciplines and activities law.invention Placebos Electroconvulsive therapy Randomized controlled trial law Antidepressants drugs Internal medicine mental disorders medicine Humans Electroconvulsive Therapy Psychiatry Depression (differential diagnoses) Randomized Controlled Trials as Topic Depressive Disorder Antidepressive Agents Psychiatry and Mental health Treatment Outcome Meta-analysis Antidepressant Psychology |
Popis: | This study analyzed the efficacy of electroconvulsive therapy (ECT) in depression by means a meta-analytic review of randomized controlled trials that compared ECT with simulated ECT or placebo or antidepressant drugs and by a complementary meta-analytic review of nonrandomized controlled trials that compared ECT with antidepressants drugs. The review revealed a significant superiority of ECT in all comparisons: ECT versus simulated ECT, ECT versus placebo, ECT versus antidepressants in general, ECT versus TCAs and ECT versus MAOIs. The nonrandomized controlled trials also revealed a significant statistical difference in favor of ECT when confronted with antidepressants drugs. Data analyzed suggest that ECT is a valid therapeutic tool for treatment of depression, including severe and resistant forms. (Reprinted with permission by J ECT 2004; 20:13–20) |
Databáze: | OpenAIRE |
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