Usefulness of pre- and post-stent optical frequency domain imaging findings in the prediction of periprocedural cardiac troponin elevation in patients with coronary artery disease
| Autor: | Hisashi Katayama, Noriaki Kasayuki, Kenichiro Otsuka, Haruo Nakamura, Kenei Shimada, Kohei Fujimoto, Hirotoshi Ishikawa, Hisateru Takeda, Minoru Yoshiyama |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Coronary artery disease 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Myocardial infarction Thrombus health care economics and organizations Aged Aged 80 and over business.industry Troponin I Fibrous cap Stent Percutaneous coronary intervention Middle Aged Prognosis medicine.disease Coronary Vessels Plaque Atherosclerotic Cardiac surgery Logistic Models medicine.anatomical_structure Conventional PCI Cardiology Female Stents Cardiology and Cardiovascular Medicine business Biomarkers Tomography Optical Coherence |
| Zdroj: | Heart and Vessels. 35:451-462 |
| ISSN: | 1615-2573 0910-8327 |
| DOI: | 10.1007/s00380-019-01512-z |
| Popis: | Cholesterol crystals (CCs) are frequently found in high-risk plaques, such as thin-capped fibroatheromas. The purpose of this study was to investigate the associations of CCs, plaque morphologies, and post-stent optical frequency domain imaging (OFDI) findings with periprocedural cardiac troponin (cTn) elevation in patients treated with percutaneous coronary intervention (PCI). This study consists of 119 patients with stable coronary artery disease (CAD) with normal cTn levels who underwent OFDI-guided PCI. Periprocedural cTn elevation was defined as an elevation of cTn ≥ × 5 times the upper reference limit after PCI. Pre- and post-stent OFDI findings, including fibrous cap thickness (FCT), presence of CCs, and parameters for lipid and calcification were analyzed. A total of 37 (31%) patients were classified into the periprocedural cTn elevation group. Compared with lesions without CCs, lesions exhibiting CCs had thinner FCT, larger lipid arc, and longer lipid length, and were more likely to have irregular protrusion and in-stent thrombus (all p |
| Databáze: | OpenAIRE |
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