Pancreatic mucinous cystic neoplasms located in the distal pancreas: a multicenter study

Autor: Jose M. Ramia, Juan del Rio Martín, Gerardo Blanco-Fernández, Miguel Cantalejo-Diaz, Fernando Pardo, Elena Muñoz-Forner, Alberto Carabias, Alba Manuel-Vazquez, Pedro J. Hernández-Rivera, Isabel Jaén-Torrejimeno, Helga K. Kälviäinen-Mejia, Fernando Rotellar-Sastre, Marina Garcés-Albir, Raquel Latorre, Texell Longoria-Dubocq, Noelia De Armas-Conde, Alejandro Serrablo-Requejo, Sara Esteban Gordillo, Luis Sabater, Mario Serradilla-Martín
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Gland Surg
Gland Surgery
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
ISSN: 2227-8575
Popis: BACKGROUND: Mucinous cysts of the pancreas (MCN) are infrequent, usually unilocular tumors which occur in postmenopausal women and are located in the pancreatic body/tail. The risk of malignancy is low. The objective is to define preoperative risk factors of malignancy in pancreatic MCN and to assess the feasibility of the laparoscopic approach. METHODS: Retrospective multicenter observational study of prospectively recorded data regarding distal pancreatectomies was carried out at seven hepatopancreatobiliary (HPB) Units between 01/01/08 and 31/12/18 (the ERPANDIS Project). RESULTS: Four hundred and forty-four distal pancreatectomies were recorded including 47 MCN (10.6%). Thirty-five were non-invasive tumors (74.5%). In all, 93% of patients were female, and 60% were ASA (American Society of Anaesthesiology) II. The mean preoperative size was 46 mm. Patients with invasive tumors were older (54 vs. 63 years). Invasive tumors were larger (6 vs. 4 cm), although the difference was not significant (P=0.287). Sixty percent was operated via laparoscopic approach, which was used in 74.6% of non-invasive tumors and in 16.7% of the invasive ones. The spleen was not preserved in 93.6% of the patients. R0 resection was obtained in all patients. Two patients with invasive tumors died. CONCLUSIONS: In our surgical series of MCN, patients with malignancy were older and presented larger tumors, although the difference was not statistically significant. Laparoscopy is a safe and feasible approach for MCN. Prospective studies are now needed to define risk factors that can guide the decision whether to administer conservative treatment or to operate.
Databáze: OpenAIRE
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