Chronic idiopathic axonal polyneuropathy: Prevalence of pain and impact on quality of life
| Autor: | Zis, Panagiotis, Sarrigiannis, Ptolemaios G., Rao, Dasappaiah G., Hewamadduma, Channa, Hadjivassiliou, Marios |
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| Přispěvatelé: | Zis, Panagiotis [0000-0001-8567-3092], Sarrigiannis, Ptolemaios G. [0000-0002-8380-8755], Hadjivassiliou, Marios [0000-0003-2542-8954], Rao, Dasappaiah G. [0000-0002-6350-8536] |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
chronic idiopathic axonal polyneuropathy medicine.medical_specialty Visual analogue scale Pain Disease Severity of Illness Index 050105 experimental psychology Axonal polyneuropathy Polyneuropathies 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine Quality of life Disease severity Surveys and Questionnaires Internal medicine Prevalence medicine Humans 0501 psychology and cognitive sciences In patient Aged Pain Measurement Original Research Aged 80 and over business.industry 05 social sciences Peripheral Nervous System Diseases Insidious onset Axons United Kingdom CIAP quality of life Etiology Female business 030217 neurology & neurosurgery |
| Zdroj: | Brain and Behavior Brain Behav |
| ISSN: | 2162-3279 |
| Popis: | Background and Aim Chronic idiopathic axonal polyneuropathy (CIAP) is a term describing axonal neuropathies of insidious onset, with slow or no progression of the disease over at least 6 months and with no etiology being identified despite appropriate investigations. We aimed to establish the prevalence of pain in patients with CIAP and investigate the impact of pain on quality of life (QoL). Methods All consecutive patients with CIAP attending a specialist neuropathy clinic were invited to participate. Pain was assessed via the DN4 questionnaire and the visual analogue scale (VAS). Overall Neuropathy Limitations Scale (ONLS) was used to assess the severity of neuropathy. The SF‐36 questionnaire was used to measure participants’ quality of life. Results Fifty‐five patients with CIAP were recruited (63.6% male, mean age 73.4 ± 8.7 years). Based on the DN4 questionnaire, peripheral neuropathic pain was present in 33 patients (60.0%). After having adjusted for age, gender and disease severity pain showed significant negative correlations with the energy/fatigue domain of QoL (β = −0.259, p = 0.049), with the emotional well‐being domain (β = −0.368, p = 0.007) and the general health perception domain (β = −0.356, p = 0.007). Conclusion Pain is very prevalent in CIAP and is associated with poorer emotional well‐being, worse general health perception, and increased fatigue. |
| Databáze: | OpenAIRE |
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