Induced pluripotent stem cells (iPSCs) derived from frontotemporal dementia patient's peripheral blood mononuclear cells

Autor:	John M. Wells, Han-Kyu Lee, Peter J. Morin, Weiming Xia, Eugene B. Hanlon
Rok vydání:	2015
Předmět:	Pathology medicine.medical_specialty viruses Cellular differentiation Genetic Vectors Induced Pluripotent Stem Cells Kruppel-Like Transcription Factors Peripheral blood mononuclear cell Proto-Oncogene Proteins c-myc Kruppel-Like Factor 4 SOX2 mental disorders medicine Humans Induced pluripotent stem cell lcsh:QH301-705.5 Medicine(all) biology SOXB1 Transcription Factors Cell Differentiation Cell Biology General Medicine Cellular Reprogramming biology.organism_classification medicine.disease Sendai virus 3. Good health lcsh:Biology (General) KLF4 Frontotemporal Dementia Karyotyping embryonic structures Immunology Leukocytes Mononuclear sense organs Octamer Transcription Factor-3 Reprogramming Developmental Biology Frontotemporal dementia
Zdroj:	Stem Cell Research, Vol 15, Iss 2, Pp 325-327 (2015)
ISSN:	1873-5061
DOI:	10.1016/j.scr.2015.07.004
Popis:	Peripheral blood mononuclear cells (PBMC) were donated by a patient with clinically diagnosed frontotemporal dementia (FTD). Induced pluripotent stem cells (iPSCs) were developed using integration-free CytoTune-iPS Sendai Reprogramming factors which include Sendai virus particles of the four Yamanaka factors Oct, Sox2, Klf4, and c-Myc.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2671bdb46b545a488c7bf0a286c66a3 https://doi.org/10.1016/j.scr.2015.07.004 Zobrazit plný text záznamu