The formalin test: A tonic pain model in the primate
| Autor: | Nayar U, Pradeep G. Mutalik, Meenakshi Alreja, S.K. Manchanda |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Restraint Physical Formalin Test Time Factors Meperidine Analgesic Pain Tonic (physiology) Formaldehyde biology.animal medicine Animals Primate Behavior Animal Morphine biology Hand Macaca mulatta Pethidine Disease Models Animal Anesthesiology and Pain Medicine Neurology Assessing Pain Anesthesia Chronic Disease Female Neurology (clinical) Psychology Palmar surface medicine.drug |
| Zdroj: | Pain. 20:97-105 |
| ISSN: | 0304-3959 |
| DOI: | 10.1016/0304-3959(84)90815-7 |
| Popis: | The formalin test has been used in monkeys for assessing pain. After formalin injection in the palmar surface of the hand just proximal to the base of the fingers, the monkey's responses are rated for 1 h according to objective behavioral criteria. The present 'tonic' pain model has a fair degree of objectivity, validity, reproducibility and quantifiability. The analgesic effects of morphine and pethidine have been evaluated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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