A Randomized Controlled Trial Comparing a Low-Residue Diet Versus Clear Liquids for Colonoscopy Preparation
| Autor: | Craig A. Solem, David R. Stolpman, Michael J. Shaw, Dianna Eastlick, S. A. Adlis |
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| Rok vydání: | 2014 |
| Předmět: |
Adenoma
Male medicine.medical_specialty Time Factors Colon Minnesota Colonic Polyps Color Colonoscopy Withdrawal time Gastroenterology law.invention Beverages Patient satisfaction Randomized controlled trial Predictive Value of Tests law Internal medicine Humans Medicine Single-Blind Method Prospective Studies Prospective cohort study Aged Aged 80 and over Chi-Square Distribution medicine.diagnostic_test Cathartics business.industry Middle Aged Diet Patient Satisfaction Predictive value of tests Colonic Neoplasms Patient Compliance Low residue diet business Chi-squared distribution |
| Zdroj: | Journal of Clinical Gastroenterology. 48:851-855 |
| ISSN: | 0192-0790 |
| DOI: | 10.1097/mcg.0000000000000167 |
| Popis: | Objective To achieve an excellent bowel preparation, it is routine to require a clear liquid diet on the day before the procedure. Unfortunately, this dietary modification may be poorly tolerated. We examine whether a change in precolonoscopy dietary restriction can lead to better patient tolerance without compromising examination quality. Methods This is a prospective, blinded, randomized controlled trial of patients undergoing screening or surveillance colonoscopy. The primary objective measures the effect of dietary modification on bowel prep quality. Secondary endpoints include polyp detection, patient tolerance, withdrawal time, and patient acceptance. A total of 200 patients were randomized to either (a) a low-residue diet for breakfast and lunch the day before the procedure or (b) clear liquids all day before the procedure. All patients underwent an identical low-volume sodium sulfate split prep. Bowel prep quality was scored using the Boston Bowel Preparation Scale (BBPS). A t test with TOST was used for noninferiority. Secondary endpoints were compared using χ analysis. Results Overall, 96.5% of patients had a good or excellent bowel prep (BBPS=6, 7, 8, or 9). LRD prep quality was noninferior to CLD prep quality (LRD 7.8 vs. CLD 8.1). Polyp detection rates were similar (68% vs. 65.4%, P=0.6899). Patient tolerance and acceptance did not differ. Withdrawal times were equivalent between both groups (16.2 vs. 16.5 min, P=NS). Conclusions Patients allowed to have a limited low-residue diet before colonoscopy achieve a bowel prep quality that is noninferior to patients on a strict clear liquid diet limitation. Furthermore, polyp detection rates, patient tolerance, and patient acceptance were similar between the 2 groups. |
| Databáze: | OpenAIRE |
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