Clinical Presentation and Management of SMART Syndrome

Autor: Eugene J Vaios, Jorg Dietrich, Eudocia Q. Lee, Helen A. Shih, Franziska Loebel, Joshua P. Klein, Philipp Karschnia, Sebastian F Winter
Rok vydání: 2021
Předmět:
Zdroj: Neurology. 97:118-120
ISSN: 1526-632X
0028-3878
DOI: 10.1212/wnl.0000000000012150
Popis: Stroke-like migraine attacks after radiation therapy (SMART) syndrome represents a rare but serious condition manifesting years after cranial radiation therapy (RT).1 Characterized by migraine-type headaches, stroke-like deficits, seizures, and MRI abnormalities, including cortical gyriform enhancement in irradiated brain regions, SMART is diagnostically and therapeutically challenging.2-6 Distinction from tumor progression is difficult and treatment options are limited.2 Although frequently reversible,5 SMART episodes can recur6 and effectuate persistent neurologic or imaging sequelae.3
Databáze: OpenAIRE