Chemically inducible inactivation of protein synthesis in genetically targeted neurons

Autor:	Kazu Nakazawa, Yuan Lu, Bai Lu, Feng Yang, Hyunsoo Shawn Je, Jianzheng Zhou, Zhihong Jiang, Guhan Nagappan
Rok vydání:	2009
Předmět:	Dendritic spine Patch-Clamp Techniques Time Factors Dendritic Spines Green Fluorescent Proteins Long-Term Potentiation Hippocampus Tacrolimus Binding Protein 1A Biology In Vitro Techniques medicine.disease_cause Transfection Tacrolimus Article Tacrolimus Binding Proteins Mice eIF-2 Kinase Protein biosynthesis medicine Animals Humans Cells Cultured Brain-derived neurotrophic factor Neurons Mutation Analysis of Variance General Neuroscience Brain-Derived Neurotrophic Factor Excitatory Postsynaptic Potentials Long-term potentiation Electric Stimulation Rats Protein Biosynthesis Synaptic plasticity Excitatory postsynaptic potential Neuroscience
Zdroj:	The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(21)
ISSN:	1529-2401
Popis:	Synaptic plasticity mediates a variety of physiological functions, including emotional regulation, drug addiction, and learning and memory ([Goelet et al., 1986][1]). There are two temporally distinct forms of synaptic plasticity: short-term plasticity, which lasts seconds to minutes, and long-term
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f254be1ed26a57c9b444c6791c0929ea https://pubmed.ncbi.nlm.nih.gov/19474302 Zobrazit plný text záznamu