Total body potassium, skeletal muscle potassium and magnesium in patients with Bartter's syndrome
| Autor: | I. Hessov, I. Bosaeus, A. Rudin |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Muscle tissue medicine.medical_specialty Potassium Clinical Biochemistry chemistry.chemical_element Bartter syndrome Reference Values Internal medicine Hyperaldosteronism Biopsy medicine Humans Magnesium medicine.diagnostic_test Muscles Bartter Syndrome Skeletal muscle General Medicine Middle Aged Total body potassium medicine.disease Bartter's syndrome medicine.anatomical_structure Endocrinology chemistry Female |
| Zdroj: | Scandinavian Journal of Clinical and Laboratory Investigation. 50:273-277 |
| ISSN: | 0036-5513 |
| DOI: | 10.3109/00365519009091578 |
| Popis: | In 20 patients with Bartter's syndrome, who had a serum potassium concentration of 2.75 +/- 0.29 mmol/l (mean +/- SD), the total body potassium (TBK) was measured and compared with a predicted value obtained from regression equations based on age, sex, body height and weight. A significant difference was found between the observed and predicted TBK (mean -320 +/- 306 mmol, p less than 0.01). A positive correlation existed between the serum potassium concentration and the ratio observed TBK/predicted TBK. However, the average fractional reduction in TBK (-11%) was less than the average fractional decrease in serum potassium concentration (-32%). Muscle biopsy specimens were obtained from four patients with Bartter's syndrome and 10 control subjects for analyses of potassium and magnesium. The serum concentrations of potassium and magnesium were decreased in these patients. The potassium content in muscle tissue was lower in two of four patients, but no difference in the amount of magnesium was observed. |
| Databáze: | OpenAIRE |
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