Accuracy of Multislice Computed Tomography in the Preoperative Assessment of Coronary Disease in Patients With Aortic Valve Stenosis

Autor: Jacques Mansourati, Grégoire Le Gal, Jean-Jacques Blanc, Jean-Christophe Cornily, Cedric Joret, Pierre-Yves Pennec, Jacques Boschat, Martine Gilard
Přispěvatelé: Service d'Hémodynamique, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-Hôpital de la Cavale Blanche - CHRU Brest (CHU - BREST ), Optimisation des régulations physiologiques (ORPHY (EA 4324)), Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Service de Cardiologie (BREST - Cardio), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Groupe d'Etude de la Thrombose de Bretagne Occidentale (GETBO), Université de Brest (UBO)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Rok vydání: 2006
Předmět:
Male
medicine.medical_treatment
Coronary Artery Disease
030204 cardiovascular system & hematology
030218 nuclear medicine & medical imaging
Coronary artery disease
MESH: Aged
80 and over

0302 clinical medicine
Aortic valve replacement
Prospective Studies
MESH: Coronary Artery Disease
MESH: Aortic Valve Stenosis
Aged
80 and over

Heart Valve Prosthesis Implantation
MESH: Aged
MESH: Middle Aged
Middle Aged
MESH: Predictive Value of Tests
3. Good health
medicine.anatomical_structure
Aortic valve stenosis
Circulatory system
Cardiology
Female
Radiology
MESH: Tomography
X-Ray Computed

Cardiology and Cardiovascular Medicine
Artery
MESH: Preoperative Care
MESH: Heart Valve Prosthesis Implantation
medicine.medical_specialty
Revascularization
03 medical and health sciences
Predictive Value of Tests
Internal medicine
Preoperative Care
medicine
Humans
Multislice
Aged
MESH: Humans
business.industry
Aortic Valve Stenosis
medicine.disease
MESH: Prospective Studies
MESH: Male
Stenosis
Tomography
X-Ray Computed

business
MESH: Female
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: Journal of the American College of Cardiology
Journal of the American College of Cardiology, Elsevier, 2006, 47 (10), pp.2020-4. ⟨10.1016/j.jacc.2005.11.085⟩
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2005.11.085
Popis: International audience; OBJECTIVES: To evaluate multislice computed tomography (MSCT) as an alternative to coronary angiography, we prospectively studied its diagnostic accuracy for the detection of significant coronary artery lesions in patients with significant aortic valve stenosis undergoing valve surgery. BACKGROUND: In patients with aortic valve stenosis, coronary angiography is still recommended before surgery. Multislice computed tomography is a promising noninvasive technique for the detection of significant coronary artery lesions. METHODS: Fifty-five consecutive patients scheduled for coronary angiography in the preoperative assessment of aortic valve stenosis underwent 16-slice MSCT 24 h before coronary angiography. We analyzed coronary lesions, image quality, and arterial calcium score. RESULTS: The sensitivity of the MSCT-based strategy in detecting significant stenosis was 100%, and its specificity 80%. The positive and negative predictive values were respectively 55% and 100%. For calcium scores 1,000, MSCT enabled conventional coronary angiography to be avoided in only 6% of cases, either because significant stenosis was found with a possible indication of revascularization, or because the examination was not interpretable. CONCLUSIONS: The results of this initial experience in relatively few patients suggest that MSCT-based coronary angiography may serve as an alternative to invasive coronary angiography to rule out significant coronary artery disease in patients scheduled for elective aortic valve replacement. Larger studies are necessary to fully explore the potential of coronary MSCT to improve preoperative risk stratification.
Databáze: OpenAIRE