The Effects of Ripe Pistachio Hulls Hydro-alcoholic Extract and Aerobic Training on Learning and Memory in Streptozotocin-induced Diabetic Male Rats
Autor: | Hasan Mohammadzadeh, Sajad Abdi Gorabi, Mohammad Rostampour |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment ripe pistachio hulls lcsh:RC321-571 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Diabetes mellitus Internal medicine Male rats medicine Aerobic exercise streptozotocin-diabetic rats Saline lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry 030304 developmental biology 0303 health sciences Clinical neuroscience medicine.disease Streptozotocin Endocrinology Neurology (clinical) Passive avoidance aerobic training learning and memory 030217 neurology & neurosurgery Research Paper Diabetic control medicine.drug |
Zdroj: | Basic and Clinical Neuroscience, Vol 11, Iss 4, Pp 525-534 (2020) Basic and Clinical Neuroscience |
ISSN: | 2228-7442 |
Popis: | Introduction: Diabetes mellitus has harmful effects on body functions, such as learning and memory. According to the role of exercise and medicinal plants on body health, the purpose of this study was to survey the effect of combined aerobic training and the use of Ripe Pistachio Hulls (RPH) hydro-alcoholic extract on learning and memory in streptozotocin-induced diabetic male rats. Methods: In this experimental study, 42 male Wistar rats weighing 250-280 g were used in 6 groups with an equal number of 7 rats in each one. Streptozotocin (STZ) (50 mg / kg)was used to induce diabetes , and the test protocol was applied for 8 weeks. Passive avoidance memory was assessed using a step-through passive avoidance apparatus (shuttle box). SPSS software was used to analyze the data and P |
Databáze: | OpenAIRE |
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