Familial ganglioneuromatous polyposis of the large bowel
| Autor: | Geoffrey Mendelsohn, Mark P. Diamond |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Colonic Polyps Gastroenterology Pathology and Forensic Medicine Internal medicine otorhinolaryngologic diseases medicine Humans Neurofibroma Ganglioneuroma Neurofibromatosis Child business.industry Juvenile Polyposis Neuroma medicine.disease digestive system diseases Ganglion Colonic mucosa medicine.anatomical_structure Colonic Neoplasms Female Surgery Anatomy business Ganglioneuromatosis |
| Zdroj: | The American Journal of Surgical Pathology. 8:515-520 |
| ISSN: | 0147-5185 |
| DOI: | 10.1097/00000478-198407000-00003 |
| Popis: | The unique familial occurrence of polypoid intestinal ganglioneuromatosis of the large bowel is reported. The lesions affected a 38-year-old father and three children aged 14, 12, and 10 years. In these cases, extensive diffuse and polypoid proliferation of nerve fibers and ganglion cells within the colonic mucosa was associated with pronounced epithelial changes resembling juvenile polyposis. None of the patients had any clinical evidence of the mucosal neuroma syndrome or Von Recklinghausen's neurofibromatosis, conditions in which intestinal ganglioneuromatosis can occur. The question of whether the juvenile-type polyps are hamartomatous or whether they represent a reactive process is addressed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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