3-Tesla MR spectroscopy in patients subjected to bone marrow transplantation: clinical correlations
| Autor: | Gme Simonetti, Amedeo Taglieri, Eleonora Gaspari, Gianluigi Sergiacomi, V. Gisone, Alessandro Meschini, W. Arcese, L. Cudillo |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male In vivo magnetic resonance spectroscopy Magnetic Resonance Spectroscopy Bone marrow transplantation Settore MED/36 - Diagnostica per Immagini e Radioterapia immune system diseases hemic and lymphatic diseases 3-Tesla magnetic resonance medicine Humans Radiology Nuclear Medicine and imaging Platelet Spectroscopy Bone Marrow Transplantation Neuroradiology Analysis of Variance medicine.diagnostic_test Platelet Count business.industry Lymphoma Non-Hodgkin Ultrasound Lumbosacral Region Magnetic resonance imaging General Medicine Middle Aged medicine.disease Lipids Lymphoma surgical procedures operative medicine.anatomical_structure Hematocrit Erythrocyte Count Bone marrow business Nuclear medicine Settore MED/15 - Malattie del Sangue |
| Zdroj: | La radiologia medica. 118:101-111 |
| ISSN: | 1826-6983 0033-8362 |
| DOI: | 10.1007/s11547-012-0796-8 |
| Popis: | This study evaluated the usefulness of 3-Tesla magnetic resonance (MR) spectroscopy in patients with non-Hodgkin’s lymphoma (NHL) undergoing bone marrow transplantation (BMT). Twelve NHL patients who were candidates for BMT underwent three MR examinations of the lumbosacral spine: before ablative therapy for BMT, 15±4 days and 54±24 days after BMT. The MR study was supplemented by spectroscopic analysis. The lipid content was calculated and expressed as a percentage of lipid signal intensity relative to total signal intensity [fat fraction (FF)]. In the first MR study, the FF was 62.5±7%, in the second it was 70.75±5% and in the third it was 75±1%. We observed a statistically significant difference between FF values calculated at the various MR studies (p=0.02) and between red blood cell count (p=0.017), platelet count (p=0.003) and haematocrit (p |
| Databáze: | OpenAIRE |
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