Combination of organocatalytic oxidation of alcohols and organolithium chemistry (RLi) in aqueous media, at room temperature and under aerobic conditions
| Autor: | Alejandro Presa Soto, Eva Hevia, Joaquín García-Álvarez, Francisco Morís, David Elorriaga, María J. Rodríguez-Álvarez, Javier González-Sabín, Nicolás Ríos-Lombardía |
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| Rok vydání: | 2020 |
| Předmět: |
Aqueous solution
Tandem Aqueous medium Metals and Alloys General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound chemistry Alcohol oxidation Reagent 540 Chemistry Materials Chemistry Ceramics and Composites 570 Life sciences biology Organic chemistry Oxidation of secondary alcohols to ketones Tertiary alcohols Organometallic chemistry |
| Zdroj: | Chemical Communications. 56:8932-8935 |
| ISSN: | 1364-548X 1359-7345 |
| Popis: | A tandem protocol to access tertiary alcohols has been developed which combines the organocatalytic oxidation of secondary alcohols to ketones followed by their chemoselective addition by several RLi reagents. Reactions take place at room temperature, under air and in aqueous solutions, a trio of conditions that are typically forbidden in polar organometallic chemistry. |
| Databáze: | OpenAIRE |
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