Similarities in electron micrographs of purified Lansing and SK poliomyelitis virus

Autor: Hubert S. Loring
Rok vydání: 2010
Předmět:
Zdroj: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 64(1)
ISSN: 0037-9727
Popis: This note is written to correct the impression which was erroneously given1 that purified SK poliomyelitis virus consists of asymmetric particles of the type described by Gard2 for a strain of Theilers mouse virus. While this conclusion was suggested by one of Bourdillon's3 experiments in which an older dialyzed, purified preparation showed double refraction of flow, the results published by Jungeblut and Bourdillon4 show a remarkable agreement between purified SK and! our purified Lansing preparations. The purified SK samples in contrast to those from unpurifiedi tissue cultures showed the presence of “spherical or elliptic bodies” having a diameter between 25 and 30 m/x. It is noteworthy that particles of the same relative size and shape have been obtained, therefore, from 2 different strains of poliomyelitis virus, both of which were isolated originally from infectious human material. As it might be expected that different human strains would have similar physical properties, the results from the 2 lab...
Databáze: OpenAIRE