Resistance Exercise Impacts Lean Muscle Mass in Women with Polycystic Ovary Syndrome
| Autor: | Rui Alberto Ferriani, Anderson Sanches de Melo, Cristiana Libardi Miranda-Furtado, Gislaine Satyko Kogure, Rafael Costa Silva, Rosana Maria dos Reis, Marcos Felipe Silva de Sá |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty Adolescent Intra-Abdominal Fat 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation Muscle mass COMPOSIÇÃO CORPORAL Young Adult 03 medical and health sciences Absorptiometry Photon 0302 clinical medicine Sex hormone-binding globulin Sex Hormone-Binding Globulin Internal medicine medicine Humans Testosterone Orthopedics and Sports Medicine Young adult Muscle Skeletal Adiposity 030219 obstetrics & reproductive medicine biology business.industry Androstenedione Resistance training food and beverages Resistance Training Exercise therapy Polycystic ovary Exercise Therapy Endocrinology biology.protein Female Waist Circumference business Polycystic Ovary Syndrome |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 0195-9131 |
| DOI: | 10.1249/mss.0000000000000822 |
| Popis: | This study investigated the effects of progressive resistance training (PRT) on lean muscle mass (LMM) in women with or without polycystic ovary syndrome (PCOS) and its effects on metabolic factors and concentrations of related steroid hormones.This was a nonrandomized, therapeutic, open, single-arm study.All in all, 45 sedentary women with PCOS and 52 without (non-PCOS), 18-37 yr of age, with body mass indexes (BMI) of 18-39.9 kg·m(-2) of all races and social status, performed PRT three times a week for 4 months. Before and after PRT, the concentrations of hormones and metabolic factors and waist circumference were measured. LMM and total body fat percentage were determined using dual-energy x-ray absorptiometry. Clinical characteristics, LMM, and fasting glucose were adjusted for confounding covariables and compared using general linear mixed models. Each patient's menstrual history was taken before study enrollment and after PRT.PRT resulted in reduced plasma testosterone and fasting glucose levels. After PRT, the androstenedione concentration increased and the sex hormone-binding globulin concentration decreased in women with PCOS. The waist circumference was reduced (P0.01) and the muscle mass index, lean mass (LM)/height2, increased in women with PCOS (P = 0.04). Women with PCOS showed increased muscle mass indexes of appendicular LM/height2 (P = 0.03) and LM/height2 (P0.01) compared with the baseline. Total LM and trunk LM were elevated in women with PCOS (P = 0.01) at the baseline and after PRT.To our knowledge, this is the first report to show that resistance exercise alone can improve hyperandrogenism, reproductive function, and body composition by decreasing visceral fat and increasing LMM, but it has no metabolic impact on women with PCOS. |
| Databáze: | OpenAIRE |
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