Impact of Postthrombotic Vein Wall Biomechanics on Luminal Flow during Venous Angioplasty and Stent Placement: Computational Modeling Results

Autor: Ningcheng Li, Jack Ferracane, Nicole Andeen, Steven Lewis, Randy Woltjer, Sandra Rugonyi, Younes Jahangiri, Barry Uchida, Khashayar Farsad, John A. Kaufman, Ramsey Al-Hakim
Rok vydání: 2022
Předmět:
Zdroj: Journal of Vascular and Interventional Radiology. 33:262-267
ISSN: 1051-0443
Popis: This study characterized the impact of vein wall biomechanics on inflow diameter and luminal flow during venous angioplasty and stent placement, using postthrombotic and healthy biomechanical properties from an ovine venous stenosis and thrombosis model. Finite element analysis demonstrated more pronounced inflow channel narrowing in the postthrombotic vein compared with the healthy control vein during angioplasty and stent placement (relative inflow diameter reduction of 42% versus 13%, P.0001). Computational fluid dynamics modeling showed increased relative areas of low wall shear rate in the postthrombotic vein compared with the normal vein (0.46 vs 0.24 for shear rate50 s
Databáze: OpenAIRE