Effects of HIV on executive function and verbal fluency in Cameroon

Autor: Anne M. Kengne, Dora M. Njamnshi, Robert K. Heaton, Roland F. Doh, Emilienne Nchindap, Anya Umlauf, Dora Mbanya, Claude Tayou Tagny, Bin Tang, Alfred K. Njamnshi, Julius Y. Fonsah, Léopoldine Kenmogne, Georgette D. Kanmogne, Donald Franklin
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
ISSN: 2045-2322
Popis: HIV-associated neurocognitive disorders (HAND) are frequently associated with impaired executive function and verbal fluency. Given limited knowledge concerning HAND in Sub-Saharan-Africa and lack of Cameroonian adult neuropsychological (NP) test norms, we administered four executive function [Halstead Category Test (HCT), Wisconsin Card Sorting Test (WCST), Color Trails-II (CTT2), and Stroop Color-Word-Interference (SCWT)] and three verbal fluency (Category, Action, and Letter Fluency) tests to 742 adult Cameroonians (395 HIV−, 347 HIV+). We developed demographically-corrected NP test norms and examined the effects of HIV and related variables on subjects’ executive function and verbal fluency. HIV+ subjects had significantly lower T-scores on CTT2 (P = 0.005), HCT (P = 0.032), WCST (P
Databáze: OpenAIRE
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