Effects of HIV on executive function and verbal fluency in Cameroon
Autor: | Anne M. Kengne, Dora M. Njamnshi, Robert K. Heaton, Roland F. Doh, Emilienne Nchindap, Anya Umlauf, Dora Mbanya, Claude Tayou Tagny, Bin Tang, Alfred K. Njamnshi, Julius Y. Fonsah, Léopoldine Kenmogne, Georgette D. Kanmogne, Donald Franklin |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Adult
Neurocognitive Disorders lcsh:Medicine HIV Infections Neuropsychological Tests Article 03 medical and health sciences Fluency Executive Function 0302 clinical medicine Cognition Acquired immunodeficiency syndrome (AIDS) Wisconsin Card Sorting Test Reference Values medicine Verbal fluency test Humans 030212 general & internal medicine Cognitive skill Cameroon lcsh:Science Language Multidisciplinary lcsh:R Neuropsychology HIV medicine.disease 3. Good health Female lcsh:Q Psychology Cognition Disorders Neurocognitive 030217 neurology & neurosurgery Clinical psychology Stroop effect |
Zdroj: | Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018) Scientific Reports |
ISSN: | 2045-2322 |
Popis: | HIV-associated neurocognitive disorders (HAND) are frequently associated with impaired executive function and verbal fluency. Given limited knowledge concerning HAND in Sub-Saharan-Africa and lack of Cameroonian adult neuropsychological (NP) test norms, we administered four executive function [Halstead Category Test (HCT), Wisconsin Card Sorting Test (WCST), Color Trails-II (CTT2), and Stroop Color-Word-Interference (SCWT)] and three verbal fluency (Category, Action, and Letter Fluency) tests to 742 adult Cameroonians (395 HIV−, 347 HIV+). We developed demographically-corrected NP test norms and examined the effects of HIV and related variables on subjects’ executive function and verbal fluency. HIV+ subjects had significantly lower T-scores on CTT2 (P = 0.005), HCT (P = 0.032), WCST (P |
Databáze: | OpenAIRE |
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