FormylBODIPYs: Privileged Building Blocks for Multicomponent Reactions. The Case of the Passerini Reaction
| Autor: | Iñigo López Arbeloa, Eduardo Peña-Cabrera, Teresa Arbeloa, Luis A. Pérez-García, Diana E. Ramírez-Ornelas, Enrique Alvarado-Martínez, Héctor M. Mora-Montes, Jorge Bañuelos |
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| Rok vydání: | 2016 |
| Předmět: |
Boron Compounds
Molecular Structure 010405 organic chemistry Chemistry Organic Chemistry 010402 general chemistry 01 natural sciences Fluorescence Passerini reaction 0104 chemical sciences chemistry.chemical_compound Cytophagocytosis Low exposure Organic chemistry Spectrophotometry Ultraviolet BODIPY Fluorescent Dyes |
| Zdroj: | The Journal of organic chemistry. 81(7) |
| ISSN: | 1520-6904 |
| Popis: | Eleven formyl-containing BODIPY dyes were prepared by means of either the Liebeskind–Srogl cross-coupling reaction or the Vilsmeier reaction. These dyes were used as components in the Passerini reaction to give highly substituted BODIPY dyes. A joined spectroscopic and theoretical characterization of the synthesized compounds was conducted to unravel the impact of the structural rigidity/flexibility on the photophysical signatures. These dyes were tested as fluorescent trackers for phagocytosis. Additionally, they proved to be useful to stain different blood cells with an intense and stable signal at a very low exposure time. |
| Databáze: | OpenAIRE |
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