Interictal depressive disorders in epilepsy patients
| Autor: | M. Suarez Gomez, A. Matos Pires, Yuri Simões Martins |
|---|---|
| Přispěvatelé: | IIFA, Universidade de Évora, Universidad de Extremadura (UEX) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
[SCCO.NEUR]Cognitive science/Neuroscience Adjustment disorders medicine.disease Irritability 3. Good health Psychiatry and Mental health Personality changes Epilepsy Quality of life [SCCO.PSYC]Cognitive science/Psychology medicine Anxiety Psychogenic disease medicine.symptom Psychiatry Psychology Depression (differential diagnoses) Clinical psychology |
| Zdroj: | European Psychiatry European Psychiatry, Cambridge University press, 2016, 33 (S1), pp.S417-S417. ⟨10.1016/j.eurpsy.2016.01.1506⟩ |
| ISSN: | 0924-9338 |
| Popis: | IntroductionDepression is recognized as more frequent psychiatric disorder in epilepsy patients with significant impact on their health-related quality of life.AimsTo analyze the occurrence and clinical particularities of different types of interictal depression in epilepsy patients.MethodsOne hundred and fourteen epilepsy patients with interictal depression were assessed with a clinical interview and Hamilton depression and anxiety rating scales. Diagnostic criteria of ICD-10 and of the International League Against Epilepsy (ILAE) were used.ResultsA total of 45.6% of patients met ILAE criteria of inerictal dysforic disorder (IDD) with predominance of depressive mood, irritability, fear and atypical pain. All patients had chronic epilepsy with specific epileptic personality changes. Comorbid adjustment disorders (depressive and anxious-depressive reactions) were diagnosed in 27.2% of patients. The most frequent trigger situations were: family problems, serious illness, unemployment, financial difficulties. In more than half of patients were registered specific personality changes whose severity was in inverse ratio with trauma severity. A total of 18.4% of patients met criteria of comorbid affective disorder (depressive and bipolar) with some specific clinical traits due to personality changes. In 8.8% of patients, anticonvulsant-induced depression was observed; it was clinically simple, resolved after offending medication withdrawal.ConclusionsObserved depressive disorders were heterogeneous: comorbid or attributed to epilepsy or its treatment. The most frequent condition was IDD. Specific personality changes may contribute to higher susceptibility and development of psychogenic depression. We emphasize the importance of treatment history (possibility of anticonvulsant-induced depression).Disclosure of interestThe authors have not supplied their declaration of competing interest. |
| Databáze: | OpenAIRE |
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