Childhood Cancer Symptom Cluster: Leukemia and Health-Related Quality of Life
| Autor: | Wei Pan, Cheryl Rodgers, Kari M. Koerner, Michael E. Scheurer, Marilyn J. Hockenberry, Pauline Mitby, Olga A. Taylor, Ida M. Moore, Mary C. Hooke |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Nausea Childhood cancer Article 03 medical and health sciences Maintenance therapy Quality of life Surveys and Questionnaires Internal medicine medicine Humans Child Depression (differential diagnoses) Health related quality of life Sleep disorder Leukemia 030504 nursing business.industry Oncology Nursing Syndrome medicine.disease United States humanities Cross-Sectional Studies Child Preschool Quality of Life Female medicine.symptom 0305 other medical science business |
| Zdroj: | Oncol Nurs Forum |
| Popis: | Objectives: To examine the relationship of the Childhood Cancer Symptom Cluster–Leukemia (CCSC-L) with health-related quality of life (HRQOL). Sample & Setting: 327 children receiving treatment for acute lymphoblastic leukemia from four pediatric oncology programs across the United States. Methods & Variables: Participants completed fatigue, sleep disturbance, pain, nausea, and depression symptom questionnaires at four time points; these symptoms comprised the CCSC-L. HRQOL was measured at the start of postinduction therapy and then at the start of maintenance therapy. Relationships between the CCSC-L and HRQOL scores were examined with longitudinal parallel-process modeling. Results: The mean HRQOL significantly increased over time (p < 0.001). The CCSC-L had a significant negative association with HRQOL scores at the start of postinduction therapy (beta = –0.53, p < 0.005) and the start of maintenance therapy (beta = –0.33, p < 0.015). Participants with more severe symptoms in the CCSC-L over time had significantly lower HRQOL at the start of maintenance therapy (beta = –0.42, p < 0.005). Implications for Nursing: Nurses are pivotal in providing management strategies to minimize symptom severity that may improve HRQOL. |
| Databáze: | OpenAIRE |
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