Improvement of post-hypoxic action myoclonus with levetiracetam add-on therapy: A case report
Autor: | Aleksandar Jesic, Ksenija Gebauer-Bukurov, Ksenija Božić, Ivana Divjak, Lorand Sakalaš |
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Rok vydání: | 2015 |
Předmět: |
Male
Myoclonus congenital hereditary and neonatal diseases and abnormalities Levetiracetam diagnosis Myoclonic Jerk Electroencephalography Fracture Fixation Internal Pharmacotherapy Fracture fixation mental disorders medicine Humans Pharmacology (medical) Hypoxia lcsh:R5-920 Zygoma drug resistance medicine.diagnostic_test business.industry Accidents Traffic anoxia Action myoclonus Middle Aged syndrome Magnetic Resonance Imaging Piracetam Clonazepam nervous system diseases drug therapy Anesthesia treatment outcome Anticonvulsants medicine.symptom business lcsh:Medicine (General) medicine.drug |
Zdroj: | Vojnosanitetski Pregled, Vol 71, Iss 5, Pp 515-519 (2014) |
ISSN: | 0042-8450 |
Popis: | Introduction. Chronic post-anoxic myoclonus, also known as Lance-Adams syndrome, may develop following hypoxic brain injury, and is resistant to pharmacological therapy. Case report. The patient we presented developed post-anoxic action myoclonus with severe, completely incapacitating myoclonic jerks. Myoclonus did not respond to the treatment with commonly used agents, i.e. valproate and clonazepam alone or in combination. Improvement of the action myoclonus was observed only after adding levetiracetam. Conclusion. Although Lance-Adams syndrome may not be fully curable at this point, levetiracetam appears to be a promising agent that can significantly improve functional level and overall quality of life of patients with this disorder. |
Databáze: | OpenAIRE |
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