Prognostic Factors for Survival in Invasive Squamous Cell Vulvar Carcinoma: A Univariate Analysis
| Autor: | V. Kouloulias, C. Loghis, L. Vlahos, C. Sykiotis, J. Kouvaris, M. Balafouta |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Risk Oncology medicine.medical_specialty Pathology Cell Vulva Internal medicine medicine Humans Neoplasms Squamous Cell Aged Neoplasm Staging Vulvar Diseases Aged 80 and over Analysis of Variance Univariate analysis Vulvar Neoplasms Life style business.industry Proportional hazards model Smoking Obstetrics and Gynecology Middle Aged Prognosis humanities Survival Rate medicine.anatomical_structure Reproductive Medicine Epidermoid carcinoma Female Vulvar Carcinoma business |
| Zdroj: | Gynecologic and Obstetric Investigation. 51:262-265 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000058061 |
| Popis: | The charts of 50 women with invasive squamous cell vulvar carcinoma were reviewed retrospectively, and pathologic, medical and life style factors were analyzed for their possible influence on survival using the Cox regression univariate model. The median age of the cohort was 73.5 years. The patient distribution according to stage was as follows: stage I: 17; stage II: 16; stage III: 12, and stage IVa: 5 patients. The median follow-up was 61 months. The univariate analysis revealed that the overall survival was decreased by age ≧73.5 years (p = 0.0185), advanced stage (p = 0.0026), grade III differentiation (p < 0.0001), ulcerative type of the tumor (p = 0.0055), tumor diameter >40 mm (p = 0.0053), obesity (p = 0.011), smoking (p = 0.0177), diabetes (p = 0.0122) and hypertension (p = 0.044), but not with clitoral involvement. |
| Databáze: | OpenAIRE |
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