No effect of adjunctive fluoxetine on eating behavior or weight phobia during the inpatient treatment of anorexia nervosa: an historical case-control study
| Autor: | Michael Strober, Caroly Pataki, Roberta Freeman, Mark DeAntonio |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Pediatrics
medicine.medical_specialty Anorexia Nervosa Adolescent medicine.medical_treatment Pharmacotherapy Fluoxetine medicine Combined Modality Therapy Humans Pharmacology (medical) Psychiatry Chemotherapy Analysis of Variance Case-control study Feeding Behavior Clinical trial Psychotherapy Psychiatry and Mental health Anorexia nervosa (differential diagnoses) Chemotherapy Adjuvant Case-Control Studies Pediatrics Perinatology and Child Health Analysis of variance Psychology Selective Serotonin Reuptake Inhibitors medicine.drug |
| Zdroj: | Journal of child and adolescent psychopharmacology. 9(3) |
| ISSN: | 1044-5463 |
| Popis: | A six-week open label clinical trial investigated the response to fluoxetine in adolescents hospitalized for treatment of anorexia nervosa. Patients were drawn from consecutive admissions to a specialty treatment service and received fluxoetine as an add-on to their multidisciplinary treatment regimen beginning three weeks to one month postintake. Global clinical severity ratings of eating behavior and weight phobia were obtained at baseline and then at biweekly intervals. These ratings were compared to those obtained from matched historical case-controls who received an identical course of inpatient therapy but without adjunctive pharmacotherapy. Analyses failed to show any beneficial or detrimental effect of fluoxetine on these clinical measures. We conclude that fluoxetine has no robust additive or synergistic therapeutic benefit when measured against the effects of intensive, multidisciplinary inpatient therapy. |
| Databáze: | OpenAIRE |
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