Greenland sledge dogs (Canis familiaris) develop liver lesions when exposed to a chronic and dietary low dose of an environmental organohalogen cocktail
| Autor: | Robert J. Letcher, Maja Kirkegaard, Christian Sonne, Soheila Shahmiri, Rune Dietz, Asger Lundorff Jensen, Pall S. Leifsson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Food Chain
medicine.drug_class Greenland Physiology Aspartate transaminase Biochemistry Dogs Blubber medicine Animals Minke whale General Environmental Science Dose-Response Relationship Drug biology Balaenoptera Bile acid Hydrocarbons Halogenated Chemistry Liver Diseases Anatomy biology.organism_classification Diet Canis Alanine transaminase Toxicity biology.protein Environmental Pollutants Chemical and Drug Induced Liver Injury Environmental Monitoring |
| Zdroj: | Sonne, C, Leifsson, P S, Dietz, R, Kirkegaard, M, Jensen, A L, Shahmin, S & Letcher, R J 2008, ' Greenland sledge dogs ( Canis familiaris ) develop liver lesions when exposed to a chronic and dietary low dose of an environmental organohalogen cocktail ', Environmental Research, vol. 106, no. 1, pp. 72-80 . https://doi.org/10.1016/j.envres.2007.08.010 |
| DOI: | 10.1016/j.envres.2007.08.010 |
| Popis: | We assessed the relationship between exposure to organohalogen polluted minke whale (Balaenoptera acutorostrata) blubber and liver morphology and function in a generational controlled study of 28 Greenland sledge dogs (Canis familiaris). The prevalence of portal fibrosis, mild bile duct hyperplasia, and vascular leukocyte infiltrations was significantly higher in the exposed group (all Chi-square: p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|