Outcome of Patients with Fortuitous Prostate Cancer after Radical Cystoprostatectomy for Bladder Cancer
| Autor: | Bernard Debré, Nicolas Barry Delongchamps, Michaël Peyromaure, Kaili Mao, Hang Theng, Marc Zerbib |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
Nephrology medicine.medical_specialty Urology medicine.medical_treatment Cystectomy urologic and male genital diseases Risk Assessment Cystoprostatectomy Cohort Studies Prostate cancer Urothelial cell carcinoma Internal medicine Humans Medicine Pathological Aged Neoplasm Staging Retrospective Studies Prostatectomy Bladder cancer Radical cystoprostatectomy business.industry Biopsy Needle Prostatic Neoplasms Neoplasms Second Primary Middle Aged Prognosis medicine.disease Immunohistochemistry Survival Rate Treatment Outcome Urinary Bladder Neoplasms Male patient business |
| Zdroj: | European Urology. 48:946-950 |
| ISSN: | 0302-2838 |
| DOI: | 10.1016/j.eururo.2005.07.008 |
| Popis: | Objectives To analyze the outcome of patients after fortuitous diagnosis of prostate cancer (PCa) on cystoprostatectomy (CPT) specimen. Methods The medical charts of 141 male patients who underwent radical CPT for urothelial cell carcinoma of the bladder between january 1995 and april 2000 were retrospectively reviewed. None of the patients had preoperative clinical or biological suspicion of PCa. Results Pathological examination of the CPT specimens showed PCa in 20 patients (14.2%). Of these, 6 had a microfocal PCa, 10 had a pT2a tumour, 2 had a pT2b tumour, and 2 had a pT3a tumour. The Gleason score was ≤5 in 5 cases, 6 in 13 cases, and 7 in 2 cases. Two patients were lost to follow-up. Ten patients died of bladder cancer after a median follow-up of 13 months. Eight patients remained free of disease after a median follow-up of 64.5 months. None of the 20 patients experienced PCa recurrence during follow-up. Conclusions In our experience, the rate of unsuspected PCa on cystoprostatectomy specimens was 14.2%. The majority of these PCas were organ-confined, and there was no PCa recurrence during follow-up. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect