Free Radical Scavenging and Some Pharmaceutical Utilities of Nanoparticles in the Recent Scenario
| Autor: | Xavier-Ravi Baskaran, Wenbo Liao, Kilimas Rajan, Shouzhou Zhang, Antony-varuvel Geo Vigila |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pharmacology
chemistry.chemical_classification 0303 health sciences Reactive oxygen species Antioxidant Chemistry medicine.medical_treatment Radical Biocompatible nanoparticles Nanoparticle Nanotechnology 02 engineering and technology Free Radical Scavengers 021001 nanoscience & nanotechnology Silver nanoparticle 03 medical and health sciences Nanomedicine Drug Discovery medicine Nanoparticles 0210 nano-technology 030304 developmental biology Free-radical theory of aging |
| Zdroj: | Current pharmaceutical design. 25(24) |
| ISSN: | 1873-4286 |
| Popis: | Background: Nanopharmaceuticals have rapidly emerged as a means to cure several diseases. There are numerous reports describing the development and application of nanopharmaceuticals. Here, we discussed nanoparticle synthesis and the mechanisms to scavenge free radicals. We also discuss their major properties and list several commercially available nanomedicines. Results: Reactive oxygen and hydrogen species are formed during normal metabolism, and excessive reactive species can damage proteins, lipids, and DNA and cause disease. Plant- and microbe-based nanoparticles, which can protect tissues from free radical damage, have recently gained research momentum because they are inexpensive and safe. Conclusion: Synthetic and biocompatible nanoparticles exhibit antioxidant, antidiabetic, anti-inflammatory, and anticancer properties, which can be used to treat several diseases. Further studies are needed to investigate their sizes, dose-dependent activities, and mechanisms of action. |
| Databáze: | OpenAIRE |
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