The influence of continuous epidural bupivacaine analgesia on the second stage of labor and method of delivery in nulliparous women
| Autor: | Won W. Chol, James N. Bates, G. E. Vandewalker, David H. Chestnut, Cindy L. Owen |
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| Rok vydání: | 1987 |
| Předmět: |
Adult
Anesthesia Epidural medicine.medical_specialty medicine.medical_treatment Analgesic Umbilical cord Random Allocation Double-Blind Method Labor Stage Second Pregnancy medicine Anesthesia Obstetrical Humans Local anesthesia Cervix Saline Bupivacaine Clinical Trials as Topic Labor Obstetric business.industry Vaginal delivery medicine.disease Delivery Obstetric Surgery Parity Anesthesiology and Pain Medicine medicine.anatomical_structure Anesthesia Female Analgesia business medicine.drug |
| Zdroj: | Anesthesiology. 66(6) |
| ISSN: | 0003-3022 |
| Popis: | A randomized, double blind, placebo-controlled study was performed to evaluate the analgesic efficacy and influence of continuing an epidural infusion of 0.125% bupivacaine beyond a cervical dilatation of 8 cm in nulliparous women. When the cervix was greater than or equal to 8 cm dilated, coded study solution was substituted for the known 0.125% bupivacaine solution. The study solution for 46 patients was 0.125% bupivacaine; 46 patients received saline. During the first stage of labor, 44 (96%) women in the bupivacaine group, and 45 (98%) in the saline group, had analgesia of excellent or good quality. During the second stage, 36 (82%) women in the bupivacaine group, versus 18 (41%) women in the saline group, had analgesia of excellent or good quality (P less than .0001). Six (13%) women in each group underwent cesarean delivery after the start of the study solution. Among the women who delivered vaginally, the mean (+/- S.D.) duration of the second stage of labor was 124 (+/- 70) min in the bupivacaine group, versus 94 (+/- 54) min in the saline group (P less than .05). Twenty-one of 40 (53%) women in the bupivacaine group, versus 11 of 40 (28%) in the saline group, underwent instrumental vaginal delivery (P less than .05). Twenty-eight of 40 (70%) women in the bupivacaine group, versus six of 40 (15%) in the saline group; had surgical perineal anesthesia for vaginal delivery (P less than .0001). There were no significant differences between groups in Apgar scores or umbilical cord blood acid-base values.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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