Preterm birth prevention in twin pregnancies with progesterone, pessary, or cerclage: a systematic review and meta-analysis
| Autor: | Sugee Korale Liyanage, Shigeru Saito, Christina K. Park, Jon Barrett, Anne Biringer, Lisa Sabatino, Alexander Jarde, Jodie M Dodd, Lucy Giglia, Prakeshkumar S Shah, Jocelynn L. Cook, Claudio Vera, Sarah D. McDonald, Joseph Beyene, Olha Lutsiv, Katharina Staub, William Mundle, Zhen Han |
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| Rok vydání: | 2016 |
| Předmět: |
Pessary
medicine.medical_specialty medicine.medical_treatment Psychological intervention MEDLINE Gestational Age CINAHL 03 medical and health sciences 0302 clinical medicine Pregnancy Risk Factors medicine Humans 030212 general & internal medicine Progesterone Cerclage Cervical Randomized Controlled Trials as Topic Mechanical ventilation 030219 obstetrics & reproductive medicine Obstetrics business.industry Obstetrics and Gynecology Pessaries 3. Good health Administration Intravaginal Treatment Outcome Meta-analysis Relative risk Pregnancy Twin Gestation Premature Birth Female Progestins business |
| Zdroj: | BJOG : an international journal of obstetrics and gynaecology. 124(8) |
| ISSN: | 1471-0528 |
| Popis: | Background About half of twin pregnancies deliver preterm, and it is unclear whether any intervention reduces this risk. Objectives To assess the evidence for the effectiveness of progesterone, cerclage, and pessary in twin pregnancies. Search strategy We searched Medline, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, and ISI Web of Science, without language restrictions, up to 25 January 2016. Selection criteria Randomised controlled trials of progesterone, cerclage, or pessary for preventing preterm birth in women with twin pregnancies, without symptoms of threatened preterm labour. Data collection and analysis Two independent reviewers extracted data using a piloted form. Study quality was appraised with the Cochrane Risk of Bias tool. We performed pairwise inverse variance random-effects meta-analyses. Main results We included 23 trials (all but three were considered to have a low risk of bias) comprising 6626 women with twin pregnancies. None of the interventions significantly reduced the risk of preterm birth overall at |
| Databáze: | OpenAIRE |
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